Humoral Response to 2 Inactivated Bluetongue Virus Serotype-8 Vaccines in South American Camelids

Serological Survey of Bluetongue Virus Serotype-8 Infect ion in South American Camelids

Background: Outbreak of bluetongue virus serotype-8 (BTV-8) infection in domestic ruminants in Northern Europe. Objective: To investigate the South American camelids’ (SAC) susceptibility to BTV-8 infection, their role in the epidemiology of the disease, and the use of currently available serological screening tests in SAC in an endemic region. Animals: Three hundred and fifty-four unvaccinated...

Colostral antibody induced interference of inactivated bluetongue serotype-8 vaccines in calves

Since its introduction into northern Europe in 2006, bluetongue has become a major threat to animal health. While the efficacy of commercial vaccines has been clearly demonstrated in livestock, little is known regarding the effect of maternal immunity on vaccinal efficacy. Here, we have investigated the duration and amplitude of colostral antibody-induced immunity in calves born to dams vaccina...

Determination of the minimum protective dose for bluetongue virus serotype 2 and 8 vaccines in sheep.

Recent outbreaks of bluetongue virus (BTV) serotypes 2 and 8 in many European countries provided an opportunity to investigate the possibility of improving the safety of the modified live vaccines administered mainly in South Africa. Modified live vaccines (MLV) released at a titre of 5 x 104 PFU/mL, raised concerns and prompted the need to determine the minimum titre which will still be pro...

Epidemiology of Bluetongue Virus Serotype 8, Germany

In Germany, bluetongue disease had not been reported before 2006. During August 2006-August 2008, >24,000 bluetongue virus serotype 8 infections were reported, most (20,635) in 2007. In 2006 and 2007, respectively, case-fatality rates were 6.4% and 13.1% for cattle and 37.5% and 41.5% for sheep. Vaccination in 2008 decreased cases.

Reproduction in South American Camelids